Transfusion Practice

19th Annual NATA Symposium

18th Annual NATA Symposium, Florence 2018The 19th Annual NATA Symposium will be held in Lisbon, Portugal, on April 12-13, 2018.

The deadline for abstract submission is January 15, 2018.

A preliminary version of the scientific programme is available.

Please click on the link below for more information
19th Annual Symposium General Information

Focused Update: Perioperative Management of Jehovah’s Witness Patients in Relation to Their Refusal of Allogeneic Blood Transfusion

Jehovah's Witness (JW) patients strictly refuse allogeneic blood transfusion (red blood cells, plasma and platelets), even in the presence of life-threatening anemia and/or coagulopathy. However, today JW patients can undergo major surgical procedures without facing an excessive risk of death—provided that a prospectively conceived and structured perioperative management is applied.

In a Nataonline Focused Update, Prof. Oliver Habler, Department of Anesthesiology, Surgical Intensive Care Medicine and Pain Therapy, Krankenhaus Nordwest GmbH, Frankfurt, Germany, reviews the perioperative management of JW patients with emphasis on the following cornerstones: (1) the preoperative optimization of cardiopulmonary status and the correction of preoperative anemia and coagulopathy, (2) the perioperative collection of autologous blood, (3) the minimization of perioperative blood loss and (4) the utilization of the organism’s natural tolerance to anemia and its acute accentuation in the case of life-threatening anemia.

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Focused update: The management of massive hemorrhage/transfusion in civilian trauma

The management of massive hemorrhage/transfusion in trauma has evolved considerably in the past few years. Based on a consensus established in 2005, several civilian trauma centers have adopted a restrictive approach to the administration of crystalloids in view of minimizing hemodilution, along with the transfusion of red blood cells (RBC), fresh frozen plasma (FFP) and platelet concentrates (PC) in a 1:1:1 ratio. In a Nataonline Focused Update, Professor Jean-François discusses the evidence supporting this strategy.

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From the Literature

Dec 14, 2017

Published: Nov 2017

Mazer CD, Whitlock RP, Fergusson DA, et al.

Restrictive or liberal red-cell transfusion for cardiac surgery.
N Engl J Med 2017;377:2133-2144.

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NATA REVIEW:
The comparison between liberal and restrictive transfusion strategies has been the topic of intense debate. To...
REVIEW by:
D. Faraoni

Published: Oct 2017

Andrews B, Semler MW, Muchemwa L, et al.

Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial.
JAMA 2017;318:1233-1240.

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NATA REVIEW:
This single-centre, randomised, controlled, non-blinded study evaluated the potential beneficial effect of an...
REVIEW by:
M. Piagnerelli

Published: Sep 2017

Boer C, Meesters MI, Milojevic M, et al.

2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.
J Cardiothorac Vasc Anesth 2017; Sep 30 [Epub ahead of print].

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NATA REVIEW:
There is growing evidence that patient blood management (PBM) is becoming "standard of care" in major surgery...
REVIEW by:
P. Van der Linden

Published: Jun 2017

Leahy MF, Hofmann A, Towler S, et al.

Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals.
Transfusion 2017;57:1347-1358.

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NATA REVIEW:
"Randomised controlled trials (RCTs) are the de facto standard for answering clinical questions, delivering the...
REVIEW by:
J. Meier

Published: Jun 2017

Mesar T, Larentzakis A, Dzik W, Chang Y, Velmahos G, Yeh DD

Association between ratio of fresh frozen plasma to red blood cells during massive transfusion and survival among patients without traumatic injury.
JAMA Surg 2017;152:574-580.

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NATA REVIEW:
Following reports from US military and civilian trauma centres, the practice of transfusing massively bleeding...
REVIEW by:
J.-F. Hardy

Published: May 2017

Bergamin FS, Almeida JP, Landoni G, et al.

Liberal versus restrictive transfusion strategy in critically ill oncologic patients: the Transfusion Requirements in Critically Ill Oncologic Patients randomized controlled trial.
Crit Care Med 2017;45:766-773.

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NATA REVIEW:
Liberal red blood cell (RBC) transfusion in critically ill oncology patients – Is liberal better in this population...
REVIEW by:
J. Stensballe