Blood Transfusion Services / Risks of Transfusion
From the Literature
Jun 20, 2013
Published: Dec 2012
Antonelou MH, Tzounakas VL, Velentzas AD, Stamoulis KE, Kriebardis AG, Papassideri IS
Effects of pre-storage leukoreduction on stored red blood cells signaling: A time-course evaluation from shape to proteome.J Proteomics 2012;76:220-238.
NATA REVIEW:
Leukocyte reduction of blood components significantly improves the quality of labile blood products by avoiding...
REVIEW by:
R. Moog
Published: Oct 2012
Vlaar AP, Hofstra JJ, Determann RM, et al.
Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case-control study.Crit Care Med 2012;40:2813-2820.
NATA REVIEW:
This is a very interesting and smart study. The study by Vlaar and colleagues helps us understand better what's...
REVIEW by:
J. A. García-Erce
Published: Sep 2012
Stapley R, Owusu BY, Brandon A, et al.
Erythrocyte storage increases rates of NO and nitrite scavenging: implications for transfusion-related toxicity.Biochem J 2012;446:499-508.
NATA REVIEW:
In their complex basic science work, the authors suggest that NO signaling plays a central role in the transfusion-related...
REVIEW by:
M. Piagnerelli
Published: Jul 2012
Caudrillier A, Kessenbrock K, Gilliss BM, et al.
Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury.J Clin Invest 2012;122:2661-2671.
NATA REVIEW:
Transfusion of blood components may cause transfusion-associated acute lung injury (TRALI) which may result in...
REVIEW by:
R. Moog
Published: Jul 2012
Joshi NV, Raftis JB, Lucking AJ, et al.
Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury.Thromb Haemost 2012;108:176-182.
NATA REVIEW:
The authors present an interesting study suggesting that human platelets prepared in blood transfusion services...
REVIEW by:
P. Rebulla
Published: Apr 2012
Belizaire RM, Prakash PS, Richter JR, et al.
Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation.J Am Coll Surg 2012;214:648-655.
NATA REVIEW:
There is currently a controversy about whether transfusion of stored RBCs results in more transfusion complications,...
REVIEW by:
R. Moog