16th Annual NATA Symposium

16th Annual NATA Symposium, Prague 2015The 16th Annual NATA Symposium on Patient Blood Management, Haemostasis and Thrombosis will take place at the Prague Congress Centre in Prague, Czech Republic, on April 16-17, 2015.

The first announcement can be downloaded in PDF or Powerpoint format.

The preliminary scientific programme is now availble, and the deadline for abstract submission is December 19, 2014.

More information on the Annual NATA Symposium

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Join NATA's goup on LinkedIn and follow NATA on Twitter (@NATAforum) to receive the latest news on patient blood management, haemostasis and thrombosis, and to participate in discussions with colleagues in the field.
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News from the Industry: White Paper – Red Cell Salvage: Current Status

Intraoperative Red Cell Salvage (RCS) was introduced in the early 1980s and rapidly gained clinical acceptance. Early RCS was done without cell washing, but washed RCS became the standard of care in cardiac surgery and other procedures.

RCS gained popularity because it did not carry the risk of transfusion-transmitted diseases, notably HIV and hepatitis B and C, and decreased demand for allogeneic blood. While both of these benefits are still true today, the increased safety profile of allogeneic transfusion as well as the presence of stable blood inventories have diminished their importance.

Nevertheless, strong clinical and economic reasons remain to use RCS. This white paper addresses these issues.
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News

Akebia Announces Dosing of First Patient in Phase 2 Study of AKB-6548 in Patients with Anemia Related to Chronic Kidney Disease Undergoing Dialysis

On September 25, 2014, Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel, proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, announced that the first patient has been dosed in a Phase 2 clinical study of AKB-6548 in patients with anemia related to chronic kidney disease (CKD) who are undergoing dialysis. AKB-6548 is being developed as a once-daily, oral therapy with best-in-class potential for the treatment of anemia related to CKD.
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From the Literature

Nov 1, 2014

Published: Oct 2014

Goodnough LT, Maggio P, Hadhazy E, et al.

Restrictive blood transfusion practices are associated with improved patient outcomes.
Transfusion 2014;54:2753-2759.

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NATA REVIEW:
This retrospective analysis evaluated the clinical impact of the implementation of a clinical decision support...
REVIEW by:
P. Van der Linden / D. Thomas

Published: Oct 2014

Adelmann D, Klaus DA, Illievich UM, et al.

Fibrinogen but not factor XIII deficiency is associated with bleeding after craniotomy.
Br J Anaesth 2014;113:628-633.

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NATA REVIEW:
Effective haemostasis in case of haemorrhage requires fibrinogen activation to form a haemostatic fibrin clot...
REVIEW by:
O. Habler

Published: Oct 2014

Tran MH, Lin DM, Wilcox T, Schiro D, Cannesson M, Milliken J

Effects of a multimodality blood conservation schema toward improvement of intraoperative hemoglobin levels and off-pump transfusions in coronary artery bypass graft surgery.
Transfusion 2014;54:2769-2774.

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NATA REVIEW:
This observational, retrospective before-and-after single-centre study reports that the reduction of intraoperative...
REVIEW by:
P. Van der Linden

Published: Oct 2014

Gombotz H, Rehak PH, Shander A, Hofmann A

The second Austrian benchmark study for blood use in elective surgery: results and practice change.
Transfusion 2014;54:2646-2657.

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NATA REVIEW:
This second Austrian benchmark study confirms the results observed in the first study published in 2007, i.e....
REVIEW by:
P. Van der Linden

Published: Oct 2014

Tavares MM, Diquattro PJ, Sweeney JD

Reduction in red blood cell transfusion associated with engagement of the ordering physician.
Transfusion 2014;54:2625-2630.

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NATA REVIEW:
This is a single-centre retrospective analysis from Rhode Island reporting the results of an active involvement...
REVIEW by:
T. Frietsch

Published: Sep 2014

Widimsky P, Motovska Z, Havluj L, et al.

Perioperative cardiovascular complications versus perioperative bleeding in consecutive patients with known cardiac disease undergoing non-cardiac surgery. Focus on antithrombotic medication. The PRAGUE-14 registry.
Neth Heart J 2014;22:372-379.

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NATA REVIEW:
There is quite some debate regarding the interruption of antithrombotic therapy in patients with cardiovascular...
REVIEW by:
M. Levi