From the Literature

Published: Jul 2016

Stevens LM, Noiseux N, Prieto I, Hardy JF

Major transfusions remain frequent despite the generalized use of tranexamic acid: an audit of 3322 patients undergoing cardiac surgery.
Transfusion 2016;56:1857-1865.

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NATA REVIEW:
With the improvements made in non-invasive cardiac therapies (e.g. percutaneous transluminal coronary angioplasty)...
REVIEW by:
D. Faraoni

Published: Jul 2016

Rahe-Meyer N, Levy JH, Mazer CD, et al.

Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy.
Br J Anaesth 2016;117:41-51.

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NATA REVIEW:
In view of the low levels of fibrinogen in various clinical circumstances associated with haemorrhage, replacement...
REVIEW by:
M. Levi

Published: Jul 2016

Froessler B, Palm P, Weber I, Hodyl NA, Singh R, Murphy EM

The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial.
Ann Surg 2016;264:41-46.

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NATA REVIEW:
In this study, patients with confirmed iron-deficiency anaemia (IDA) scheduled for major abdominal surgery (mostly...
REVIEW by:
M. Muñoz

Published: Jul 2016

Barillari G, Londero AP, Brenner B, et al.

Recurrence of venous thromboembolism in patients with recent gestational deep vein thrombosis or pulmonary embolism: Findings from the RIETE Registry.
Eur J Intern Med 2016;32:53-59.

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NATA REVIEW:
This paper looks at the recurrent VTE rate in women who had VTE during pregnancy. As with all data from observational...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Baharoglu MI, Cordonnier C, Salman RA, et al.

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.
Lancet 2016;387:2605-2613.

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NATA REVIEW:
Essential reading for all. A reminder that however logical a therapy might be (giving platelets to those with...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Larsen TB, Skjøth F, Nielsen PB, Kjældgaard JN, Lip GY

Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.
BMJ 2016;353:i3189.

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NATA REVIEW:
Another article providing real-world data on DOACs compared with warfarin. Helpful also in comparing efficacy...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Leal-Noval SR, Muñoz-Serrano Á, Arellano-Orden V, et al.

Effects of red blood cell transfusion on long-term disability of patients with traumatic brain injury.
Neurocrit Care 2016;24:371-380.

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NATA REVIEW:
In this retrospective observational study, Leal-Noval et al. found better long-term (1-year) functional...
REVIEW by:
T. Frietsch

Published: Jun 2016

Gonzalez E, Moore EE, Moore HB, et al.

Goal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assays.
Ann Surg 2016;263:1051-1059.

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NATA REVIEW:
In a pragmatic RCT, Gonzalez and colleagues from Denver, CO, USA, show that resuscitation guided by a viscoelastic...
REVIEW by:
J. Stensballe

Published: Jun 2016

Shuvy M, Mewa J, Wolff R, et al.

Preprocedure anemia management decreases transfusion rates in patients undergoing transcatheter aortic valve implantation.
Can J Cardiol 2016;32:732-738.

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NATA REVIEW:
The authors sought to assess the impact of a preoperative blood conservation approach in treating anaemia and...
REVIEW by:
J.-F. Hardy

Published: Jun 2016

Daurat A, Roger C, Gris J, et al.

Apheresis platelets are more frequently associated with adverse reactions than pooled platelets both in recipients and in donors: a study from French hemovigilance data.
Transfusion 2016;56:1295-1303.

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NATA REVIEW:
Platelets (PLT) for transfusion can be obtained by apheresis or by whole-blood donation. Pooling of buffy coats...
REVIEW by:
R. Moog

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