From the Literature

Published: Nov 2017

Mazer CD, Whitlock RP, Fergusson DA, et al.

Restrictive or liberal red-cell transfusion for cardiac surgery.
N Engl J Med 2017;377:2133-2144.

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NATA REVIEW:
The comparison between liberal and restrictive transfusion strategies has been the topic of intense debate. To...
REVIEW by:
D. Faraoni

Published: Oct 2017

Andrews B, Semler MW, Muchemwa L, et al.

Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial.
JAMA 2017;318:1233-1240.

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NATA REVIEW:
This single-centre, randomised, controlled, non-blinded study evaluated the potential beneficial effect of an...
REVIEW by:
M. Piagnerelli

Published: Sep 2017

Boer C, Meesters MI, Milojevic M, et al.

2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery.
J Cardiothorac Vasc Anesth 2017; Sep 30 [Epub ahead of print].

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NATA REVIEW:
There is growing evidence that patient blood management (PBM) is becoming "standard of care" in major surgery...
REVIEW by:
P. Van der Linden

Published: Sep 2017

Di Angelantonio E, Thompson SG, Kaptoge S, et al.

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors.
Lancet 2017; Sep 20 [Epub ahead of print].

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NATA REVIEW:
A sufficient blood supply enables life-saving transfusions for many clinical situations, mostly in trauma and...
REVIEW by:
R. Moog

Published: Jun 2017

Mesar T, Larentzakis A, Dzik W, Chang Y, Velmahos G, Yeh DD

Association between ratio of fresh frozen plasma to red blood cells during massive transfusion and survival among patients without traumatic injury.
JAMA Surg 2017;152:574-580.

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NATA REVIEW:
Following reports from US military and civilian trauma centres, the practice of transfusing massively bleeding...
REVIEW by:
J.-F. Hardy

Published: Jun 2017

Leahy MF, Hofmann A, Towler S, et al.

Improved outcomes and reduced costs associated with a health-system-wide patient blood management program: a retrospective observational study in four major adult tertiary-care hospitals.
Transfusion 2017;57:1347-1358.

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NATA REVIEW:
"Randomised controlled trials (RCTs) are the de facto standard for answering clinical questions, delivering the...
REVIEW by:
J. Meier

Published: May 2017

Bergamin FS, Almeida JP, Landoni G, et al.

Liberal versus restrictive transfusion strategy in critically ill oncologic patients: the Transfusion Requirements in Critically Ill Oncologic Patients randomized controlled trial.
Crit Care Med 2017;45:766-773.

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NATA REVIEW:
Liberal red blood cell (RBC) transfusion in critically ill oncology patients – Is liberal better in this population...
REVIEW by:
J. Stensballe

Published: Mar 2017

White MC, Longstaff L, Lai PS

Effect of pre-operative anaemia on post-operative complications in low-resource settings.
World J Surg 2017;41:644-649.

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NATA REVIEW:
This study reports on the impact of anaemia upon surgical outcome by retrospectively analysing a cohort of 2073 patients...
REVIEW by:
B. Clevenger

Published: Mar 2017

Barile L, Fominskiy E, Di Tomasso N, et al.

Acute normovolemic hemodilution reduces allogeneic red blood cell transfusion in cardiac surgery: a systematic review and meta-analysis of randomized trials.
Anesth Analg 2017;124:743-752.

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NATA REVIEW:
This meta-analysis, which includes 29 randomised controlled trials for a total of 2439 patients, evaluates...
REVIEW by:
P. Van der Linden

Published: Mar 2017

Ad N, Holmes SD, Patel J, et al.

The impact of a multidisciplinary blood conservation protocol on patient outcomes and cost after cardiac surgery.
J Thorac Cardiovasc Surg 2017;153:597-605.

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NATA REVIEW:
This before-and-after study confirms that a standardised intraoperative blood conservation programme including...
REVIEW by:
P. Van der Linden

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