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Surgical Techniques

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Erythropoietin and Iron

Intravenous Iron

Acute Normovolemic Hemodilution

Fluid Replacement

Oxygen Carriers

Autologous Blood Donation

Cell Salvage

Hemostasis and Thrombosis

Aprotinin

Factor VIIa

The Hemophiliac Patient

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Cell Salvage in operations for gynaecological malignany (1 message)
By: Dr Smruta Shanbhag
Sub-specialty trainee
Gynaecological Oncology
James Cook University Hospital
Middlesbrough, UK
- 24-10-2007 - 12:18
I am a sub-specialty trainee and my query is regarding use of cell salvage in gynaecological cancer operations.

1. During these operations, most of the blood loss is saoked up using mops and swabs rather than large volumes in the suction.

2. The area in which we operate can involve opening the cervix/ vagina/ bowel.

3. The malignancy usually is advanced enough to involve the abdominal contents - peritoneum, omentum and bowel.


A brief literature search for cell salvage in these operations has not revealed much, as most operations are for...

Benign tumor and ethical problems and intraopeative blood salvage and follow up (1 message)
By: Sannaa China - 11-06-2007 - 15:37
Dear sir,
I’m a doctor from Beijing. I’m very interested in intraoperative blood salvage(IBS). Currently, cancer surgery is considered as contraindication to IBS for the worry about dissemination of tumor cells. Some benign tumor such as meningioma and so on also can metastasis through blood circulation in rare condition. However, the first series of utility of IBS is used in resection for meningioma, and till now IBS is still routinely used in meningioma surgery in some countries. Is it an appropriate practice? Will it be approved internationally? If we want to determine the safety of ...

Re: Article - Blood Transfusions and Alternatives in the Neonate (1 message)
By: Alejandro Padron, MD
Clinical Hematologist-Hemotherapist
Navy Medical Center
Callao, Lima, Perú
- 11-05-2007 - 17:20
Dear Sirs: Could you tell me what is the actual recomendation of the maximum time of storage of RBC for tranfusion in newborns? Than you in advance indeed. ...

Protocol for oral iron (1 message)
By: Stephen Townley
Consultant anaesthetist
Preop assessment
Royal Hampshire County Hospital
Winchester, UK
- 25-03-2007 - 22:57
Does anyone follow/have a protocol for pre-op oral iron therapy?
dose?
duration?
triggers?

problems?
compliance?

thanks...

Tuberculosis (1 message)
By: Oushimi Munasur
Perfusionist
Johannesburg General Hospital
South Africa
- 05-02-2007 - 14:18
Are there any contraindications to cell salvage in a patient with active tuberculosis, TB in the spine, and lungs, and HIV positive patients? ...

Cell saver use instead of typing and crosmmatching (3 messages)
By: Larry Turner
Total Blood Management
Sr. Autotransfusionist
Lanham, MD, USA
- 12-04-2003 - 04:20
I am in the midst of talking with some hospitals about using the cell saver in all surgeries where you have to type and crossmatch a patient. I have been told that on a national average the cost to type and crossmatch a patient is about $600.00. If we could do a standby procedure (resevoir & suction) rather than typing and crossmatching on every patient it would save the hospital and the patient money. Your feedback would be appreciated....

Errores en Medicina Transfusional (1 message)
By: Jorge Bove Perdomo
Especialista en medicina Transfusional
Hospital San José
San Jose,Uruguay
- 31-08-2006 - 04:29
Hola son médico especialista en Medicina Transfusional de Uruguay me desempeño como Jefe del Servicio de Medicina Transfusional Departamental de San Jose que tiene un promedio de donaciones de 3000 en el año con servicios de atencion de tercer nivel para abastecer de productos sanguineos.
Quiero recibir inforamcion sobre estudios sobre vigilancia y prevencion de errores en la practica transfusional, de cualquier tipo
No me refiero a reacciones adversas sino a errores tecnicos administrativos, etc....

Re: Article - Commentary: The Risk Associated With Aprotinin in Cardiac Surgery (4 messages)
By: Dave Royston
Cardiothoracic Anaesthesia
Royal Brompton and Harefield NHS Trust
Harefield, UK
- 18-02-2006 - 12:41
The article by Mangano and co-workers (1) challenges the excellent safety profile of aprotinin, and over 25 randomized trials including a meta-analysis and a Cochrane Collaboration summary which found no significant differences in mortality, myocardial infarction, or renal failure risk, and a reduced risk of stroke and a trend toward reduced postoperative atrial fibrillation (2,3).

The database did not include information on antithrombotic drugs given before operation, cardiopulmonary bypass times, operative details, blood transfusions, and perioperative data including periods of hypo...

Cell salvage in oncology (4 messages)
By: Alan Rayner
Chief Clinical Perfusion Scientist
London Bridge Hospital
HCA International
London
SE1 2PR
United Kingdom
- 14-02-2004 - 10:07
The literature regarding the use of cell salvage in oncologic procedures suggests the use of radiation and leucocyte filtration. I would be grateful if those utilising radiation would describe the protocol for this process i.e. start of salvage to transfusion of product. If you would prefer to respond personally please contact me on:
Alan.Rayner@LBH.HCAHealthcare.co.uk
Thank you in advance....

Non-Blood Thoracoabdominal Aneurysm Repair (1 message)
By: Albert Ho
Patient
California,USA
- 04-04-2006 - 05:11
I am a 46-year-old male Jehovah's Witness with Marfan's syndrome and a chronic type B aortic dissection. I have had 3 previous bloodless surgeries to repair: 1) aortic root aneurysm and aortic and mitral valves (1985), 2) aortic arch aneurysm (pericardial patch 1999) and 3) thoracic aorta aneurysm (2005). All 3 previous surgeries were performed by Dr. Craig Miller at Stanford Hospital. I still have an aneurysm of 6.8 cm in my abdominal aorta that needs to be repaired, but Dr. Miller says that it is not bad enough to risk surgery without the use of blood transfusions. I have tried many Bloodle...

vasoplegia (2 messages)
By: sadanand - 03-06-2004 - 14:33
Is vasoplegia possible after fluid therapy?...

Frozen autologous blood for transfusion vitality (2 messages)
By: Robert Marcus
Idant Labs
New York City
212/330-8511
- 28-09-2005 - 23:05
Allogeneic transfusions still present serious concerns. Pre-donated autologous blood offers greater protection from viruses and contaminants, but can adverserly affect a patient's health, recovery and outcome by allowing him or her to go into surgery anemic and hypovolemic. By freezing and storing your blood (up to ten years for RBCs) and having it delivered for a scheduled surgery, patients can go into an operation without anemia, a lower blood volume and with autologous units of fresh blood available during and after surgery. This procedure is enhanced further when patients are treated with...

Re: Article - Commentary: The Risk Associated With Aprotinin in Cardiac Surgery (1 message)
By: Robert J. Porte, MD, PhD
Department of Surgery, Section Hepatobiliary Surgery and Liver Transplantation

Herman G.D. Hendriks, MD, PhD
Department of Anesthesiology

University Medical Center Groningen, The Netherlands
- 15-02-2006 - 20:03
Dear editors,

We fully agree with Dr. Fergusson that we should not immediately abandon the use of aprotinin. He correctly summarizes the limitations and potential bias of the study by Mangano et al (1). The results of the Canadian BART trial will be extremely important and should be awaited before making definitive conclusions (2).

We have used aprotinin in our liver transplant program since 2000. If there is any group of patients that is prone for the development of renal failure, it is the group of cirrhotic patients undergoing liver transplantation. Cirrhosis itself is a...

Re: Article - Commentary: The Risk Associated With Aprotinin in Cardiac Surgery (1 message)
By: Virginia Brown
Cardidac Anaesthetist
St. Bartholomew's amd LCH and RLH
London, UK
- 09-02-2006 - 18:01
The article by Mangano in NEJM will have a huge impact on clinical practice and in particular in cardiac anaesthesia. Looking more in depth in the statistical analysis there are serious gaps and questions. Unless the interpretation of data in the article is publicly and repeatedly challenged this observational study will remain the last evidence for Aprotinin use and will affect the way we conduct anaesthesia in the future....

Particles in processed blood (5 messages)
By: Liang Hui
Department of Anesthesiology
Tian Tan Hospital
Bei Jing, China
- 08-12-2002 - 11:24
I have found some debris and particles in the processed blood under SES. Most of them are bone chips. I know this problem is difficult to solve in neurosurgeries or orthopedic operations, because the cell-washing systems are not able to completely remove the particles whose densities are similar or higher than red blood cells. The filter within the reservoir can only prevent the particles larger than 30 μm (Cobe Brat 2) mixing with the blood. So I wonder whether the particles will harm the patient. Do you have any reports or documents associated with the problem of cell washing? I wonder ...

Erythropoietin and oral iron for myelodysplasia (1 message)
By: Ricardo Benzadon, MD
Hematologist
CEMIC
Buenos Aires, Argentina
- 01-12-2005 - 16:08
Patients with Myelodysplasia (specially RA with only one cytopenia as anemia)have good responses to high doses of EPO when their endogenous EPO is low, thus remaining free from transfusion. However, some experts argue that one should administer intravenous iron for better results although their ferritin levels are high. In my experience I use oral iron and get good results too (no transfusion dependent patients). Has anyone had the same experience?...

Can oral replace intravenous iron in patients with EPO? (1 message)
By: Ricardo Benzadon, MD
Hematologist
Buenos Aires, Argentina
- 24-11-2005 - 14:38
Patients with myelodysplastic syndromes (mostly Refractory Anemia with one cytopenia) are given Erythropoietin to diminish transfusions. Although their Ferritin levels are always high it is advised to give them intravenous iron in order to increase erythropoiesis after exogenous erythropoietin is began. But little is known about the timing to begin with iron and about oral and dosage administration instead of intravenous. In my experience with the use of oral iron I have had good results but I would like to know the experiance of others with the use of oral iron in this setting....

a question on the use of FFP in neurosurgery (1 message)
By: crista - 23-09-2005 - 08:52
I am a doctor from Beijing, China. I’m very interested in blood conservation especially in neurosurgery. Neurosurgery is a kind of surgery that haemostatic function should be maintained very well because minor hemorrhage often associates with devastating effects. A platelet count of higher than 100 x 109/L has been recommended for those with multiple trauma or central nervous system injury (Development Task Force of the College of American Pathologists, 1994; Horsey, 1997). Some experts also recommend that in such surgery the use of FFP can not strictly base on the guidelines - FFP ...

Cost of Intraoperative Cell Salvage and Washing (5 messages)
By: Dale F. Szpisjak, MD
US Naval Hospital Rota, Spain
- 24-12-2002 - 12:33
I am searching for data regarding the costs of an autotransfusion service:

1. If the service is contracted, what is the cost per case assuming the contractor provides all equipment and disposables?

2. How much is the patient billed?

3. If a cell saver tech is contracted or hired by a hospital that supplies equipment, what is the salary of that technician?

4. Does the hospital's medical director of the cell salvage service receive compensation for this additional duty? If so, how much?

Thank you very much....

Transfusion alternatives in head and neck surgery (1 message)
By: Ms. Adelola
ENT, Head/neck Surgery
Midwestern Regional Hospital
Limerick, Ireland
- 13-05-2005 - 14:25
I am doing my resident traing in Otolaryngology in Ireland. I would like to know what transfusion alternatives one can use for major head and neck sugeries, such as thyroidectomy, neck dissection, and in post tonsillectomy haemorrhage. I would also like to know if there's anyone who has experience in these areas. Thank you...

USA Multicenter Prehospital PolyHeme Trial (1 message)
By: Rich Stocker
Archeology
formerly: Texas A&M University
and University of Texas, El Paso
-now retired
- 20-04-2005 - 18:24
Could someone provide me with a summary of the points made by Dr. Ernest E. Moore during his presentation at the just past 6th Annual NATA Symposium in the Czech Republic? I would love to hear more about the progress of the clinical trial he discussed: The USA Multicenter Prehospital PolyHeme Trial

And, secondarily, if anyone can give any short summaries of the following presentations from the Symposium, I would be most grateful:

TRANSFUSION AND ALTERNATIVES IN TRAUMA
Oliver Habler, Frankfurt am Main, Germany
Ivan Herold, Mlada Boleslav, Czech Rep...

Preoperative predictor factors in orthopaedic surgery (both knee and hip replacements) (1 message)
By: Susan Cottrell
Transfusion Practitioner
Scotland
- 15-12-2004 - 21:25
I am currently looking at developing protocols for our orthopaedic surgeons and am interested in any research or information relating to preoperative predictor markers which could predict post operative transfusion.

Any help would be greatly appreciated....

Erythropoietin in cancer patients (2 messages)
By: Ernil Hansen, MD PhD
Professor of Anaesthesiology
University of Regensburg, Germany
- 14-12-2002 - 19:41
Erythropoiesis is iron-dependent. Most cancer patients are iron-deficient, so iron substitution is usually necessary in erythropoietin therapy. Many tumors are iron-dependent, in some of the patients this even is the reason for their anemia.
What about the danger of enhancing tumor growth or activating disseminated tumor cells by erythropoietin/iron therapy in cancer patients ?...

Platelet Gel (2 messages)
By: Alan Rayner
Chief Clinical Perfusion Scientist
London Bridge Hospital
HCA International
London
SE1 2PR
United Kingdom
- 14-02-2004 - 08:55
Over the last few years there has been a great deal of interest in the use of autologous platelet gel and fibrin sealants in surgery and wound care. I would like to know what the NATA community and in particular the experts have to say about this. I am concerned that there has not been a proportional increase in the literature and that a lot of the published work seems to assume a benefit in one speciality based on work done in another. I am not criticizing the concept, I simply want to match my enthusiasm with evidence. If you have any comments that you would rather discuss personally please ...

Availability of IV iron (3 messages)
By: Angelina Gapay, MD
Anesthesiology
Divine Word Hospital
Tacloban city, Philippines
- 16-12-2003 - 13:59
For years we had IM iron sorbitol (Jectofer) as the only parenteral iron preparation available to our anemic patients. This year, the production of this iron preparation was stopped by ASTRA pharmaceuticals. We are at a loss of what to use. Would somebody help us secure an IV iron preparation for our patients here in the Philippines? ...

Oral iron (1 message)
By: Tracey Hall
Specialist Practitioner of Transfusion
Alder Hey Children's Hospital
Liverpool, England
- 26-02-2004 - 12:46
I am looking for information on dosage and duration of oral iron preoperatively for Orthopaedic patients.
I work in a paediatric hospital where it is felt that blood transfusion could be avoided using a combination of ANH and iron therapy pre op. These children will obviously not want IV iron and so oral iron is our only alternative.
Has anybody done any work in this field?
...

Hemochromatosis (1 message)
By: Karen Scalici, RN
Bloodless Program Coordinator
St John Detroit Riverview Hosp
USA
- 17-02-2004 - 00:02
Upon researching the use of IV iron I have read numerous articles refering to iron overload and Hemochromatosis, especially hereditary. I would like to know how to treat patients with this disease when they have blood loss anemia and at what iron levels should you not administer iron? ...

Irradiated Cell Salvage (2 messages)
By: S. Kenny MSc RN
Perioperative Blood Conservation Coordinator
Winnipeg, Canada
- 11-02-2004 - 17:45
I am interested in the use of irradiated cell salvage for surgical oncology procedures. The AABB does not have a protocol/policy for this (yet?). Does anyone utilize this process and would you be willing to share information?...

Lab values and iron replacement therapy (2 messages)
By: Deborah Tolich, RN
Director, Regional Center for Blood Conservation
St. Vincent Charity Hospital
Cleveland, OH
United States
- 29-08-2003 - 00:10
I am looking for information to explain the following:
Hemoglobin/Hematocrit normal
Serum iron normal
Total iron binding capacity normal
Transferrin saturation very low

I have internists who are treating these situations with iron?...

Cell Saver vs ConstaVac (2 messages)
By: David Pernell - 31-10-2003 - 21:42
I was wondering, is there any information published regarding the advantage of using Cell Saver instead of a ConstaVac system? ...

Aids in Africa -- Modifying HB1298 to include support for transfusion alternatives (2 messages)
By: Ben A. Pedersen, P.E. Layman U.S. - 02-05-2003 - 07:04
The recently passed US House Bill to spend $US15B on Aids in Africa will now go to the Senate. Please join me in calling for an amendment to the bill to extend financial support to ensure safe transfusion practice and the availability of transfusion alternatives.

I recommend the amendment of HB 1298 to include language which goes beyond the current "`(E) assistance to ensure a safe blood supply and sterile medical equipment; and" of Sec 301(a) to add assistance to ensure safe transfusion practice and the availability of transfusion alternatives.

This is...

AUTOTRANSFUSION (2 messages)
By: Kim - 02-10-2003 - 20:01
I was wondering if there is any needed medical experience to be an autotransfusionist cell salvage operator?...

Intravenous iron and infection (1 message)
By: Dr Joana Garcia
Anesthesia and reanimation
Hospital del Mar-Esperanza, IMAS
Barcelona, Spain
- 09-02-2004 - 17:43
What do you think about intravenous iron in a pacient with any active infection? I had been told not to do so because iron may increase infections. Many publications say so, but under theorical considerations. Also, in these publications pacients suffer from renal failure.
But what do you think about IV iron in postoperative, infected patients?...

When to transfuse FFP? (1 message)
By: Crista
Anesthesiology
- 01-02-2004 - 06:25
Many guidelines have advocated that FFP (fresh frozen plasma) should be transfused after blood loss exceeding 100% total blood volume in the condition of massive hemorrhage. Before blood loss beyond 1 blood volume, packed red blood cells and colloid solutions can be used to maintain oxygen transition capacity and blood volume. However, I think that the total protein concentration may decrease significantly to an abnormal level before blood loss exceeding 100% total blood volume, and make the blood volume difficult to be maintained stably. Furthermore, the colloid solutions most often used in o...

What effect do different fluids have? (1 message)
By: N. French Student - 19-12-2003 - 00:20
If a premature child has a bloodtest done 2 1/2 hours after birth, with Hb 11, Hct 35%, how can one be sure whether this child has lost blood, and therefore has a low Hgb, or the child's Hb/Hct is low because of hemodilution, after infusion of Tribonat 8 mL, Albumin 4% 5 mL, Glycose 12% 4 mL, 3.5 mL rinse?
How can one be sure if no Hct is taken before infusions and there is no obvious blood loss?...

Hydroxyethylstarch and delayed histamine release (2 messages)
By: Angelina Gapay, MD
Anesthesiology
Divine Word Hospital
Tacloban City, Philippines
- 16-12-2003 - 13:39
A speaker from Germany recently gave a lecture on crystalloids and colloids and cautioned us that starch solutions should not be used as they produce coagulopathy, renal problems, itching and delayed histamine release. He also told us that gelatins are a better choice in the presence of capillary leak.

This is the first time I have heard of histamine release after starch administration. I am not aware of any studies on this issue. Please elucidate....

Choice of type of aorta valve for a patient with Thalassemia (1 message)
By: Louis DROUSIE
Hospital Liaison Committee
Hainaut - Belgium
- 02-12-2003 - 11:46
I am a member of a H.L.C. in Belgium. I am looking for documentation about the choice of a valve for an aorta valve replacement for a patient who suffers from Thalassemia. The literature shows that a mechanic valve destroys more red blood cells than an organic one. Would you have information on which kind of valve is the best in such a case?
Louis Drousie
(l.drousie@tiscali.be or clh.hainaut@wol.be)
+32-477.379.274...

Hydrogen Peroxide (3 messages)
By: Ollie - 07-02-2003 - 19:36
Does anyone know of any contra-indication for Cell Salvage when using hydrogen peroxide as the disinfectant during orthopedic procedures? I understand that amniotic fluids, clotting agents, microfibrillar collagen and others are contra-indicated, but don't know about hydrogen peroxide.

Please help. ...

Which solution to wash collected blood? (3 messages)
By: Liang Hui
Department of Anesthesiology
Tian Tan Hospital
Bei Jing, China
- 08-12-2002 - 11:30
Can I use colloid solution (such as Gelofusine or HES) to wash the collected blood? And has it any advantages over 0.9% NaCl? As a washing solution, has Ringer sodium lactate any advantages over 0.9% NaCl? Because the Ringer solution contains calcium, it may activate the coagulation system, and make the quality of the processed blood poorer. Is it the case in clinical situations?

(I am currently researching intraoperative blood salvage (IBS) in craniotomies. The cell-washing systems I am using are Haemonetics Cell Saver 5, Cobe Brat 2, and Fresenius CATS.)...

Re: Article - History and Development of Transfusion Medicine (1 message)
By: Frank Thompson
England
- 05-11-2003 - 14:59
The article states:

The Old Testament contains several references to the life of the flesh being in the blood and admonishes the children of Israel neither to eat it nor to "pour it upon the earth as water." (Deuteronomy 12:23-24.)

If you check the Biblical passage referenced, you will find that, rather than adminishing the Israelites NOT to pour it upon the earth, it actually adminishes them to do just that! The idea is that the blood should be poured upon the earth RATHER THAN being eaten.

The importance of this verse is that it plays...

Re: Article - Blood management after bilateral total knee arhtroplasty (1 message)
By: Dr Kaialash Mehta
Consultant
Transfusion Medicine
Fortis Heart& Multispeciality Hospital
Punjab, India
- 05-11-2003 - 07:00
The authors of the study need to be complimented and their recommendations are in line with our experience. Most of the patients undergoing bilateral knee arthroplasty required 2 units of blood provided the pre-op. Hb levels were 12-13 g/dL.

Two units of autologus blood was sufficient in our setup and further allogeneic blood was only transfused in case the Hb dropped below 9 g/dL postoperatively. However, collecting autologus blood is not always possible in our setup for various reasons in most of the cases. About 75% of our patients undergoing bilateral knee replacement required 2 ...

Re: Article - Factors affecting transfusion of fresh frozen plasma, platelets, and red blood cells during elective coronary artery bypass graft surgery. (1 message)
By: Dr Kailash Mehta
Consultant
Transfusion Medicine
Fortis Heart Institute
Punjab, India
- 27-10-2003 - 06:46
This study is good and will improve the responsiveness of the transfusion services in predicting the transfusion requirements. We have been communicating more frequently with our cardiac surgical team and have gathered some useful experience. Open communication in common Clinical forums does help a great deal in bringing down the transfusion requirements in CABG cases.

Baseline hemoglobin levels are indeed important and this is in contrast to the hemoglobin level intra- and post-operatively wherein the Hb level should be read along with the PVO2 and extraction ratios and a s...

Autotransfusion in a cesarean section on a Jehovah's Witness (2 messages)
By: Tabitha L. Stephens, CM
Clinical Manager, Autotransfusion
Fresenius Medical Care- EA
United States
- 31-01-2003 - 06:32
I am looking for information on using a closed-circuit autotransfusion machine on a pregnant Jehovah's Witness patient with extensive uterine fibroids. The re-infusion of amniotic fluid is 100% fatal in the readings I have found. I am looking for information on this subject since I am unfamiliar with this type of situation....

Re: Article - Intervention to promote appropriate blood use in India. (1 message)
By: Dr Kailash Mehta
Consultant Transfusion Medicine
Fortis Heart and Multispeciality Hospital
- 07-06-2003 - 14:28
I am a Transfuion Consultant in the Largest tertiary care Cardiac Hospital in North India. We practised Blood Conservation techniques in our Cardiac programme and brought down the requirments of blood many folds from an average 4 units per open Heart Surgery case to an average of 1.2 units. The main thrust area was to heighten the clinical threshhold. However we have also been able to do about 35% cases of open-heart surgery without blood. This of course included cases being done off pump.
The FFP and Random Donor Platelets requirements have also been drastically bought down by stre...

Aspirin and Surgery (3 messages)
By: Juan V. Llau, MD
Senior Anesthesiologist
Hospital Clínic Universitari
Valencia, Spain
- 12-05-2003 - 01:43
It is common to stop aspirin in most (nearly all) patients that are going to be operated 5-7 days before surgery. Some recently published papers suggest that aspirin should be stopped two days before surgery. What do you think?
Indeed, if we stop aspirin 5-7 days before surgery, do we need to begin another antiplatelet agent (a short-action APA) as flurbiprofen 50 mg/12 h as in French practice?
Thank you for your opinions.
...

Re: Article - The Changing Transfusion Practice of Neonatal and Pediatric Surgery (1 message)
By: Svetlana Kotzeva
Residence doctor of anesthesiolgy and intensive care
Institute of Emergency medicine "Pigorov"
Bulgaria
- 12-04-2003 - 14:22
I am a resident doctor in anesthesiology and intensive care in an istitute for emergency medicine in Sofia, Bulgaria. I wouldd like to learn and read more about transfusion practice of neonatal and pediatric surgery, as I undergo my specialization in such a clinic. Thank you in advance. My e-mail adress is: svetlanakotzeva@abv.bg....

Hyperthermic limb perfusion for melanoma (1 message)
By: Jan Castro Graziani
Center for Bloodless Medicine and Surgery
Our Lady of the Resurrection Medical Center
Chicago, Illinois USA
- 07-04-2003 - 22:53
Could someone please advise me regarding what to suggest as the prime for the machine used in isolated limb perfusion. It must be an oxygen carrier and yet the patient does not want blood components used. If you have any other information regarding this procedure I would appreciate it....

Hypotensive Epidural Anesthesia In Practice (2 messages)
By: Y. Yavlyanskiy, M.D. - Anesth - 02-12-2002 - 15:21
Three European hospitals (Salzburg General Hospital, Kanton Hospital in St Gallen and Aarhus Hospital in Denmark) are known to use Hypotensive Epidural Anesthesia (HEA). I would be interested in hearing other anesthesiologists' opinions about their experience with HEA. I would also be interested to know whether other hospitals use HEA and what the results are. ...

Intraoperative blood salvage in surgery of benign tumors (1 message)
By: Liang Hui, MD
Department of Anesthesiology
Tian Tan Hospital
Beijing, China
- 17-01-2003 - 13:59
Surgery of malignant tumors is considered a contradiction to intraoperative blood salvage (IBS). Can IBS be safely used in surgery of benign tumors such as meningioma? Some benign tumors can also be recurrent or be metastasized to other places of the body. For example, most meningiomas are benign, but they can also metastasize to lung, liver or bones. So I worry about the safety of IBS in these operations, especially for the resection of meningioma. I would like to know the opinions of experts on this matter. Are there any studies on this issue?...

Morphologic changes of salvaged RBCs (1 message)
By: Liang Hui
Department of Anesthesiology
Tian Tan Hospital
Bei Jing, China
- 08-12-2002 - 11:18
I want to test the quality of processed blood. The test values include the morphologic changes of the processed red blood cells under scanning electron scope (SES). I have found slight to moderate morphologic alterations in some processed red cells, mostly in the forms of folds and echinocytic projections. I want to know what the exact mechanism is. Among the factors: vacuum suction, shearing stress, low concentration of plasma protein in the overdiluted blood in the reservoir, short of energy supply and inflammatory factors : which one plays the main role?

(I am currently researching...

Factor VII expression (1 message)
By: Federico Steiner - 25-11-2002 - 15:43
Question:
Does anyone know of any cultured cell lines or tissue specimens that have been shown to have no basal expression for Factor VII that I may use as a negative control for RT-PCR and Western blot?...




   



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Surgical Techniques

Transfusion Practice

Erythropoietin and Iron

Intravenous Iron

Acute Normovolemic Hemodilution

Fluid Replacement

Oxygen Carriers

Autologous Blood Donation

Cell Salvage

Hemostasis and Thrombosis

Aprotinin

Factor VIIa

The Hemophiliac Patient

Anesthesia Techniques

Oncology