|
|
 |
|
Hemoglobin Based Oxygen Carriers: Current Status and Future Directions
On April 28-29, a public workshop entitled "Hemoglobin Based Oxygen Carriers: Current Status and Future Directions" was held in Bethesda, MD, USA. This workshop sponsored by the Food and Drug Administration; the National Heart, Lung and Blood Institute, National Institutes of Health; and the Department of Health and Human Services’ Office of the Secretary and Office of Public Health and Science (OS/OPHS) featured presentations and roundtable discussions led by experts from academic institutions, government, and industry. The objective of the meeting was to discuss the safety of hemoglobin-based oxygen carriers (HBOCs) as related to a variety of potential uses of these investigational products. To consult the agenda, please click on the link above.
More on this story
4299
|
Transfusion and Hemostasis in Cardiac Surgery—An Update
The supplement to the March 2008 issue of Transfusion addresses hemostasis and blood management in cardiac surgical patients with an update of current perspectives. The Dannemiller Memorial Educational Foundation designates this educational activity for a maximum of 1.75 AMA PRA Category 1 Credit(s)TM. For more information about this educational offering, click on the link above.
More on this story
4283
|
TATM Special Issue on Blood Substitutes
The December 2007 issue of TATM, edited by Dr. Marcos Intaglietta, provides a very comprehensive overview of the current status of oxygen carriers. To access the issue, please click on the link above.
More on this story
4258
|
NATA Membership 2008
To become a NATA member or renew your membership, please click on the link above (you may also contact Stephen Smith from Wiley-Blackwell Publishing Membership Services (+44 1865 476016).
NATA membership includes a one year print and online subscription to Transfusion Alternatives in Transfusion Medicine, a reduced registration fee for the annual NATA symposia and the right to participate in the NATA General Assembly.
More on this story
4251
|
Important Trasylol Safety Information
On November 5, Bayer announced that it will temporarily suspend worldwide marketing of Trasylol (aprotinin injection) until the final results from the Canadian BART trial have been evaluated. The company elected to take this global action following direction from the German BfArM and requests from the FDA, Health Canada and other regulators that Bayer temporarily suspend Trasylol marketing in their respective countries until final BART data were available. The BART trial, a randomized controlled trial in high-risk cardiac surgery patients, was halted after a planned periodic data analysis showed reduced bleeding but also increased all-cause mortality in patients who received aprotinin compared to patients who received either epsilon-aminocaproic acid or tranexamic acid.
More on this story
4243
|
New Guidelines: Diagnosis and Management of Iron Deficiency and Anemia in IBD
New guidelines on Diagnosis and Management of Iron Deficiency and Anemia in Inflammatory Bowel Diseases will be presented on October 29 during the 15th United European Gastroenterology Week. The session, chaired by Prof. Christoph Gasche, will feature presentations on the prevalence and impact of anemia and iron deficiency in IBD (S. Kulnigg, Austria), lessons learned from animal models (B. Oldenburg, the Netherlands), anemia evaluation (A. Dignass, Germany), triggers and targets of anemia therapy (D. Rampton, UK), and treatment of iron deficiency and anemia (G. Van Assche, Belgium). These new guidelines will also be presented by Prof. Gasche during the 9th Annual NATA Symposium in Lisbon.
More on this story
4220
|
Safety of Aprotinin in Cardiac Surgery
Since January, 2006, the US FDA has been conducting a safety review of Trasylol (aprotinin injection). The review was triggered by the results of two published research studies: one that reported an increase in the chance of kidney failure, heart attack and stroke in patients treated with Trasylol compared to those treated with other similar drugs, and the other that reported an increase in kidney dysfunction compared to another drug. On September 21, 2006, FDA held a public meeting of the Cardiovascular and Renal Drugs Advisory Committee to discuss the safety and overall risk-benefit profile for Trasylol. At that meeting, the committee discussed the findings from the two published observational studies, the Bayer worldwide safety review, and the FDA review of its own post-marketing database.
On September 27, 2006, Bayer Pharmaceuticals told FDA that it had conducted an additional safety study of Trasylol. The preliminary findings from this new observational study of patients from a hospital database reported that use of Trasylol may increase the chance for death, serious kidney damage, congestive heart failure and strokes. FDA was not aware of these new data when it held the September 21, 2006, Advisory Committee meeting on Trasylol safety. FDA is actively evaluating these new data and their implications for appropriate use of the drug.
More on this story
4133
|
TATM: A New Beginning
NATA is pleased to announce that it has entered into a publishing partnership with Blackwell Publishing. TATM, the official journal of NATA since 1999, is currently being be re-launched, with an expanded editorial board and many new and exciting features for both readers and authors, including a new design and layout, online submission via Manuscript Central, Online Early (accepted articles available online before print publication), and online journal available via Blackwell Synergy (TATM Vol. 8 No. 1, dedicated to transfusion and alternatives in orthopedic surgery, is now online). To visit the new TATM home page, please click on the link above.
More on this story
4126
|
Late Breaking Session: Reevaluating the Role of Aprotinin in Cardiac Surgery
Following the publication of the study by Mangano et al. in the January 26, 2006 issue of The New England Journal of Medicine, the NATA Board of Directors has decided to organize a late breaking session entitled "Reevaluating the Role of Aprotinin in Cardiac Surgery" during the 7th Annual NATA Symposium. To consult the program of the session, please click on the link above.
More on this story
4070
|
Advances in Blood Management Strategies During the Perioperative Care
During the 7th Annual NATA Symposium, you are invited to attend a lunchtime satellite symposium entitled "Advances in Blood Management Strategies During the Perioperative Care". This symposium is chaired by Prof. Hans E. M. Kerkkamp, Utrecht, The Netherlands, and supported by a grant from Ortho Biotech. For more information on the scientific program, please click on the link above.
More on this story
4066
|
|
|
|
TATM Journal
