16th Annual NATA Symposium

16th Annual NATA Symposium, Prague 2015The 16th Annual NATA Symposium on Patient Blood Management, Haemostasis and Thrombosis will take place at the Prague Congress Centre in Prague, Czech Republic, on April 16-17, 2015.

The first announcement can be downloaded in PDF or Powerpoint format.

The preliminary scientific programme is now availble, and the deadline for abstract submission is December 19, 2014.

More information on the Annual NATA Symposium

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News from the Industry: White Paper – Red Cell Salvage: Current Status

Intraoperative Red Cell Salvage (RCS) was introduced in the early 1980s and rapidly gained clinical acceptance. Early RCS was done without cell washing, but washed RCS became the standard of care in cardiac surgery and other procedures.

RCS gained popularity because it did not carry the risk of transfusion-transmitted diseases, notably HIV and hepatitis B and C, and decreased demand for allogeneic blood. While both of these benefits are still true today, the increased safety profile of allogeneic transfusion as well as the presence of stable blood inventories have diminished their importance.

Nevertheless, strong clinical and economic reasons remain to use RCS. This white paper addresses these issues.
Read more on this

News

Akebia Announces Dosing of First Patient in Phase 2 Study of AKB-6548 in Patients with Anemia Related to Chronic Kidney Disease Undergoing Dialysis

On September 25, 2014, Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel, proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, announced that the first patient has been dosed in a Phase 2 clinical study of AKB-6548 in patients with anemia related to chronic kidney disease (CKD) who are undergoing dialysis. AKB-6548 is being developed as a once-daily, oral therapy with best-in-class potential for the treatment of anemia related to CKD.
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From the Literature

Oct 26, 2014

Published: Oct 2014

Vonk AB, Meesters MI, van Dijk WB, et al.

Ten-year patterns in blood product utilization during cardiothoracic surgery with cardiopulmonary bypass in a tertiary hospital.
Transfusion 2014;54:2608-2616.

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NATA REVIEW:
Vonk et al. describe the blood-conservation strategies and the overall consumption of red blood cells...
REVIEW by:
J.-F. Hardy

Published: Oct 2014

Shander A, Javidroozi M, Naqvi S, et al.

An update on mortality and morbidity in patients with very low postoperative hemoglobin levels who decline blood transfusion.
Transfusion 2014;2688-2695.

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NATA REVIEW:
This retrospective study reports that severe anaemia (nadir haemoglobin levels below 5-6 g/dL), when blood...
REVIEW by:
P. Van der Linden

Published: Oct 2014

Frank SM, Wick EC, Dezern AE, et al.

Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
Transfusion 2014;54:2668-2677.

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NATA REVIEW:
This is a very interesting retrospective, risk-adjusted, clinical outcome study examining the application of...
REVIEW by:
C. Vagianos

Published: Oct 2014

Bennett-Guerrero E, Kirby BS, Zhu H, Herman AE, Bandarenko N, McMahon TJ

Randomized study of washing 40- to 42-day-stored red blood cells.
Transfusion 2014;54:2544-2552.

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NATA REVIEW:
This preliminary study compared the effectiveness of two different systems for RBC washing, a point-of-care device...
REVIEW by:
G. Inghilleri

Published: Sep 2014

Pieracci FM, Stovall RT, Jaouen B, et al.

A multicenter, randomized clinical trial of IV iron supplementation for anemia of traumatic critical illness.
Crit Care Med 2014;42:2048-2057.

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NATA REVIEW:
In this multicentre randomised controlled trial, the authors investigated the effect of intravenous iron sucrose...
REVIEW by:
S. R. Leal-Noval

Published: Aug 2014

Leuchter RH, Gui L, Poncet A, et al.

Association between early administration of high-dose erythropoietin in preterm infants and brain MRI abnormality at term-equivalent age.
JAMA 2014;312:817-824.

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NATA REVIEW:
Some experimental studies suggest that erythropoietin can improve the outcome of preterm infants at risk of encephalopathy...
REVIEW by:
J. Lacroix