17th Annual NATA Symposium

16th Annual NATA Symposium, Prague 2015The 17th Annual NATA Symposium on Patient Blood Management, Haemostasis and Thrombosis was held in Dublin, Republic of Ireland, on April 14-15, 2016.

More information will be posted on Nataonline shortly.

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News from the Industry: White Paper – Red Cell Salvage: Current Status

Intraoperative Red Cell Salvage (RCS) was introduced in the early 1980s and rapidly gained clinical acceptance. Early RCS was done without cell washing, but washed RCS became the standard of care in cardiac surgery and other procedures.

RCS gained popularity because it did not carry the risk of transfusion-transmitted diseases, notably HIV and hepatitis B and C, and decreased demand for allogeneic blood. While both of these benefits are still true today, the increased safety profile of allogeneic transfusion as well as the presence of stable blood inventories have diminished their importance.

Nevertheless, strong clinical and economic reasons remain to use RCS. This white paper addresses these issues.
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News

Anaesthesia Supplement on ‘Transfusion, Thrombosis and Management of Bleeding’

Anaesthesia, the journal of the Association of Anaesthetists of Great Britain & Ireland, announces the publication of a special open-access supplement on Transfusion, Thrombosis and Management of Bleeding, to coincide with the UK launch of Patient Blood Management in the NHS.

A collaboration between anaesthetists, haematologists, surgeons and others, this supplement pulls together state-of-the-art research and recommendations into a comprehensive guide. World-renowned specialists have contributed a series of detailed reviews and debates.
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From the Literature

May 29, 2015

Published: May 2015

Goldstein JN, Refaai MA, Milling TJ, Jr., et al.

Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial.
Lancet 2015;385:2077-2087.

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NATA REVIEW:
The use of vitamin K antagonists, such as warfarin, has been increasing over the last decades and despite...
REVIEW by:
M. Levi

Published: May 2015

Dias JD, Norem K, Doorneweerd DD, Thurer RL, Popovsky MA, Omert LA

Use of thromboelastography (TEG) for detection of new oral anticoagulants.
Arch Pathol Lab Med 2015;139:665-673.

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NATA REVIEW:
In this experimental study, Dias et al. investigated whether thrombelastography (TEG) could detect and...
REVIEW by:
S. R. Ostrowski

Published: Apr 2015

Sentilhes L, Lasocki S, Ducloy-Bouthors AS, et al.

Tranexamic acid for the prevention and treatment of postpartum haemorrhage.
Br J Anaesth 2015;114:576-587.

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NATA REVIEW:
This systematic review provides a good summary of trials evaluating tranexamic acid (TXA) for the prevention...
REVIEW by:
B. J. Hunt

Published: Apr 2015

Pisani A, Riccio E, Sabbatini M, Andreucci M, Del Rio A, Visciano B

Effect of oral liposomal iron versus intravenous iron for treatment of iron deficiency anaemia in CKD patients: a randomized trial.
Nephrol Dial Transplant 2015;30:645-652.

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NATA REVIEW:
In this randomised, open-label trial, 99 patients with non-dialysis chronic kidney disease (ND-CKD) and iron...
REVIEW by:
M. Muñoz

Published: Mar 2015

Ponikowski P, van Veldhuisen DJ, Comin-Colet J, et al.

Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency.
Eur Heart J 2015;36:657-668.

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NATA REVIEW:
The authors studied the benefits and safety of long-term intravenous iron therapy in patients with heart failure...
REVIEW by:
L. T. Goodnough

Published: Mar 2015

Murphy GJ, Pike K, Rogers CA, et al.

Liberal or restrictive transfusion after cardiac surgery.
N Engl J Med 2015;372:997-1008.

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NATA REVIEW:
Murphy et al. conducted a very large (2003 patients) randomised trial comparing a liberal (threshold...
REVIEW by:
J.-F. Hardy